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Table 3 Summary of palliative systemic therapy in treated patients

From: Patterns of care for patients with advanced soft tissue sarcoma: experience from Australian sarcoma services

Systemic therapy line, n (%a) Treatment details
First-line (n = 86, 100 %) Single-agent chemtoherapy (n = 62, 72 %)
Doxorubicin (n = 43)
Clinical trial (n = 7)
Ifosfamide (n = 4)
Paclitaxel (n = 3)
Other (n = 5)
Combination therapy (n = 24, 28 %)
Doxorubicinb and ifosfamide (n = 13)
Clinical trial (n = 7)
Other combination (n = 4)
Second-line (n = 38, 44 %) Single-agent chemtoherapy (n = 35, 92 %)
Ifosfamide (n = 20)
Dacarbazine (n = 5)
Pazopanib (n = 3)
Clinical trial (n = 3)
Other (n = 4)
Combination therapy (n = 3, 8 %)
Third-line (n = 20, 23 %) Single-agent chemtoherapy (n = 18, 90 %)
Pazopanib (n = 6)
Dacarbazine (n = 6)
Cyclophophamide (n = 3)
Other (n = 3)
Combination therapy (n = 2, 10 %)
Fourth-line (n = 6, 7 %) Single-agent chemtoherapy (n = 6, 100 %)
Pazopanib (n = 2)
Doxorubicin (n = 1)
Ifosfamide (n = 1)
Cyclophophamide (n = 1)
Trabectedin (n = 1)
Fifth-line (n = 1, 1 %) Pazopanib (n = 1)
  1. aThe percentage refers to the proportion of patients who received the corresponding line treatment out of the total number treated with systemic therapy (n = 86)
  2. bOne patient had epirubicin and ifosfamide